The control of stem cell division and differentiation is crucial to ensure correct development of an embryo and to maintain tissue homeostasis during adult life. Dysregulation of these processes causes birth defects and diseases such as cancer. We have identified a crucial role for a proteoglycan, called syndecan, in the development of stem cells. The project will involve working with an experienced postdoctoral fellow in analysing stem development using immunofluorescence and confocal microscopy. In addition, the student will perform genetic and molecular analysis to help identify the molecular mechanisms through which syndecan controls stem cell development. Only extremely dedicated and driven students with excellent oral and written communication skills should apply.
Stem cells, syndecan proteoglycan, biology, mitosis, apoptosis C. elegans, Department of Anatomy & Developmental Biology,
Biomedicine Discovery Institute (School of Biomedical Sciences) » Anatomy and Developmental Biology
Masters by research
Top-up scholarship funding available