Research Projects
The problem: Picture this… Cheng is an 83-year-old woman living with dementia in a residential aged care facility (RACF), she has frequent falls....
Supervisor: Adj Clin Prof Diana Egerton-Warburton
The currently identified genetic prostate cancer risk factors account for less than 40% of the familial risk for the disease. Very few of these...
Supervisor: Professor Melissa Southey
Known genetic risk factors for prostate cancer include rare genetic variants in prostate cancer predisposition genes that are associated with high to...
Supervisor: Professor Melissa Southey
For over 100 years the need to understand particular disease causing, bacterial isolates to treat disease has been clearly understood. Importantly,...
Supervisor: Assoc Prof Sam Forster
Epilepsy is a severe neurological disorder characterized by recurrent seizures that affect 1% of the population worldwide. Traumatic brain injury (...
Supervisor: A/Prof Pablo Casillas-Espinosa MD, PhD
The ankle is a clinically important weight-bearing joint, and damage at this site is relevant to osteoarthritis, post-traumatic joint disease, and...
Supervisor: Associate Professor Ayse Zengin
RASopathies that are caused by germ-line mutations affecting genes residing along the canonical MAPKinase signaling pathway. They constitute the...
Supervisor: Fabrice Jaffré
hiPSC technology coupled with genome editing technology (CRISPR) offers an unprecedented opportunity to study patient-specific disease in a dish....
Supervisor: Fabrice Jaffré
In collaboration with a Maternal-Fetal Medicine colleague from the United States who has been working on the role of Human Leukocyte Antigens (HLA)...
Supervisor: Daniel Rolnik
The MACPF/CDC family proteins use a common fold to oligomerise into a ring-shaped transmembrane pore capable of either direct cell lysis or passive...
Supervisor: Assoc Professor Michelle Dunstone
Contemporary treatment of multiple myeloma and acute lymphoblastic leukaemia (ALL) still relies heavily on steroids (glucocorticoids - like...
Supervisor: Professor Jake Shortt
This study examines the mental health outcomes for people who are treated in a novel, post-suicide attempt outreach program. The program is one of...
Supervisor: Adj ClinAssProf Judith Hope
Hospital admissions can expose older adults to a spectrum of avoidable and costly harms. Not least of these is hospital-associated functional decline...
Supervisor: Associate Professor Christina Ekegren
Immunity to malaria is slow to develop due to the rapid induction of regulatory cell responses that hamper adaptive immunity. Type I IFN signalling...
Supervisor: A/Prof Michelle Boyle
The strongest predictor of experiencing a severe COPD exacerbation (flare-up) requiring hospital admission is having had a severe exacerbation in the...
Supervisor: Professor Anne Holland
Male and female brains differ in anatomy and chemistry The prevailing dogma that oestrogen is the key factor involved in brain sex differentiation...
Supervisor: Professor Vincent Harley
This study will be undertaken in collaboration with health care providers in palliative care and addiction services. The palliative care of people...
Supervisor: Ms Katrina Recoche
Injury creates a fertile environment allowing for plasticity mechanisms to shape recovery. The ability of the brain to reorganize synaptic...
Supervisor: Dr Nafiseh Atapour
Skeletal muscle is the largest tissue by mass in the human body and yet there is a major clinical gap in the lack of treatments for diseased muscle....
Supervisor: Meagan McGrath
*** Background ***
Some diagnostic tests and screening are overused and cause overdiagnosis. This can lead to avoidable patient harms and healthcare...
Supervisor: Mr Tomas Rozbroj