Research Projects
hiPSC technology coupled with genome editing technology (CRISPR) offers an unprecedented opportunity to study patient-specific disease in a dish....
Supervisor: Fabrice Jaffré
In collaboration with a Maternal-Fetal Medicine colleague from the United States who has been working on the role of Human Leukocyte Antigens (HLA)...
Supervisor: Daniel Rolnik
The MACPF/CDC family proteins use a common fold to oligomerise into a ring-shaped transmembrane pore capable of either direct cell lysis or passive...
Supervisor: Assoc Professor Michelle Dunstone
Contemporary treatment of multiple myeloma and acute lymphoblastic leukaemia (ALL) still relies heavily on steroids (glucocorticoids - like...
Supervisor: Professor Jake Shortt
This study examines the mental health outcomes for people who are treated in a novel, post-suicide attempt outreach program. The program is one of...
Supervisor: Adj ClinAssProf Judith Hope
Hospital admissions can expose older adults to a spectrum of avoidable and costly harms. Not least of these is hospital-associated functional decline...
Supervisor: Associate Professor Christina Ekegren
Immunity to malaria is slow to develop due to the rapid induction of regulatory cell responses that hamper adaptive immunity. Type I IFN signalling...
Supervisor: A/Prof Michelle Boyle
The strongest predictor of experiencing a severe COPD exacerbation (flare-up) requiring hospital admission is having had a severe exacerbation in the...
Supervisor: Professor Anne Holland
Male and female brains differ in anatomy and chemistry The prevailing dogma that oestrogen is the key factor involved in brain sex differentiation...
Supervisor: Professor Vincent Harley
This study will be undertaken in collaboration with health care providers in palliative care and addiction services. The palliative care of people...
Supervisor: Ms Katrina Recoche
Injury creates a fertile environment allowing for plasticity mechanisms to shape recovery. The ability of the brain to reorganize synaptic...
Supervisor: Dr Nafiseh Atapour
Skeletal muscle is the largest tissue by mass in the human body and yet there is a major clinical gap in the lack of treatments for diseased muscle....
Supervisor: Meagan McGrath
*** Background ***
Some diagnostic tests and screening are overused and cause overdiagnosis. This can lead to avoidable patient harms and healthcare...
Supervisor: Mr Tomas Rozbroj
Pulmonary rehabilitation is a critical treatment for people with chronic obstructive pulmonary disease (COPD) that improves exercise capacity and...
Supervisor: Professor Anne Holland
Cells need to know when enough nutrients and lipids are available to grow. Our recent work identified GPR155 as an unexpected cholesterol-sensing...
Supervisor: Professor Andrew Ellisdon
Gastric cancer is a leading cause of cancer-related death, claiming more than 1 million lives annually. A major predisposing factor to developing...
Supervisor: Dr Dustin Flanagan
Congenital heart defects are the most common type of birth defect, affecting approximately 1 in 500 live births. Many of these disorders involve...
Supervisor: Dr. Renee Chow
A process of primary care renewal is evolving across the developed world. It is increasingly recognised that high performing primary care that has a...
Supervisor: Professor Grant Russell
Heart valve stenosis is a common and life-threatening disease in which the heart valves become thickened and stiff, restricting blood flow and...
Supervisor: Dr. Renee Chow
The acquisition of resistance to therapies by cancer cells, sadly, is often inevitable. To effectively treat cancer, we need to understand how...
Supervisor: Dr Omer Gilan