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Research Projects

The mammalian oocyte is the largest cell in the body and undergoes two highly specialised asymmetric meiotic cell divisions. Coordination of...

We have identified specific sphingolipids that control brain development and protect the nervous system throughout life. This exciting project will...

The Combes laboratory has opportunities for postgraduate research projects in animal and stem cell models of kidney development and disease, advanced...
Supervisor: Dr Alex Combes

The prevalence of diabetes mellitus continues to increase worldwide leading to premature mortality. About 30% of patients with type 2 diabetes (T2D)...

Neurogenesis describes the fundamental process of generating neurons that integrate into existing circuits. Although originally thought to cease...

The transcript encoding the proto-oncogene MYC is commonly overexpressed in prostate cancer (PC). MYC protein abundance is also increased in the...
Supervisor: Dr Luc Furic

Background: Strong climatic changes may have been the primary drivers of human evolution. Understanding how early human (hominin) foraging and...
Supervisor: A/Prof Luca Fiorenza

Thin, flat, branched actin cytoskeleton filled membrane protrusions like the lamellipodia and membrane ruffles are utilized by cells for a plethora...
Supervisor: Dr Senthil Arumugam

The shape of the lower jaw (mandible) and dentition in non-human primates varies between species but the reasons behind this morphological variation...

Neuroanatomy is a critical, yet notoriously difficult, subject in medical education, essential for linking complex neural pathways to clinical signs...
Supervisor: Yasith Mathangasinghe

This study investigates the role of Smad3 acetylation in the development and progression of organ/tissue fibrosis.

The thymus is primarily responsible for generating naïve, self-tolerant T cells from hematopoietic precursors. However, deterioration of thymic...

Background: Polycystic kidney disease (PKD) is the most common potentially lethal Mendelian disease, affecting around 1/1000 people. It arises when...

Prostate cancer is a global health challenge. Many patients with prostate cancer have positive outcomes, but some patients develop aggressive tumours...
Supervisor: Dr Mitchell Lawrence

A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have...

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