Research Projects
HIV maturation is a highly regulated process, and viral protease has to cleave precursor of the main structural protein Gag in a sequential manner....
Supervisor: Assoc Professor Alex De Marco
Cellular aging is a complex biological process involving a gradual decline in cellular function and increased vulnerability to disease. It is...
Supervisor: Dr Iman Azimi
Non-ribosomal peptide synthesis is a complex biosynthetic process that produces many medically important peptide natural products, including several...
Supervisor: Assoc Professor Max Cryle
FIKK kinases are unique among apicomplexan parasites. Interestingly the genome of P. falciparum encodes 20 FIKK kinases, but very little is known...
Supervisor: Professor Brian Cooke
Clostridium difficile is recognised as the major cause of nosocomial diarrhoea in Australian hospitals and in hospitals worldwide. Chronic colitis...
Supervisor: Professor Dena Lyras
The spleen is an important organ of the immune system and it is often removed for the treatment of different medical conditions, to perform surgery...
Supervisor: Dr Gabriela Khoury
Background:
Polycystic kidney disease (PKD) is the most common potentially lethal Mendelian disease, affecting around 1/1000 people. It arises when...
Supervisor: Assoc Professor Ian Smyth
Antibiotics are a precious and diminishing resource. There is a desperate need to reduce or replace the use of antibiotics to treat bacterial...
Supervisor: Professor Dena Lyras
One of the major areas of interest in our laboratory is the importance of chemokines and their receptors in the regulation of immune responses and...
Supervisor: Dr Remy Robert
Throughout life exposure to a vast array of pathogens shapes our immune system to establish a repertoire of specific memory T cells that can be...
Supervisor: Dr Nicole Mifsud
For decades the immune system and the nervous system were thought to be completely cut off from one another. This was thought to be the explanation...
Supervisor: Leon Smyth
Bats carry and transmit numerous deadly viruses to humans and harbour many unique immunological adaptations allowing them to host viruses without...
Supervisor: Dr. Joshua A. Hayward
Almost 40%-50% of melanoma patients do not respond or can develop resistance to current checkpoint inhibition immunotherapy. While antigen-based...
Supervisor: Chen Li
Prostate cancer is a global health challenge. Many patients with prostate cancer have positive outcomes, but some patients develop aggressive tumours...
Supervisor: Dr Mitchell Lawrence
Dendritic cells (DCs) are sentinel immune cells endowed with the unique capacity to initiate antigen specific immunity and tolerance. Owning their...
Supervisor: MICHAEL CHOPIN, PHD
Caloric vestibular stimulation (CVS) is a simple, safe, inexpensive bedside neuromodulation technique that has been shown to induce a wide range of...
Supervisor: Dr Steven Miller
A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have...
Supervisor: Professor Kieran Harvey