Research Projects
DC monitor the environment for potential “danger signals” that signify pathogen invasion, including non-homeostatic cell death caused by viruses. We...
Supervisor: Assoc Professor Mireille Lahoud
Thin, flat, branched actin cytoskeleton filled membrane protrusions like the lamellipodia and membrane ruffles are utilized by cells for a plethora...
Supervisor: Dr Senthil Arumugam
The shape of the lower jaw (mandible) and dentition in non-human primates varies between species but the reasons behind this morphological variation...
Supervisor: Dr Olga Panagiotopoulou
The presentation of post-translationally modified (PTM) peptides by cell surface MHC molecules increases the diversity of targets for recognition by...
Supervisor: Dr Nathan Croft
Neuroanatomy is a critical, yet notoriously difficult, subject in medical education, essential for linking complex neural pathways to clinical signs...
Supervisor: Yasith Mathangasinghe
It is well-established that neurons in the whisker area of somatosensory cortex and thalamus exhibit directional selectivity. Direction preference is...
Supervisor: Dr Mehdi Adibi
Our mothers programed the first decisions of our lives by mRNA dumping: the regulated translation of this maternal transcriptome controls the first...
Supervisor: Prof Traude Beilharz
Monoclonal antibodies (mAbs) that block checkpoint inhibitory receptors including Programmed Death (PD)-1 act directly on T cells to overcome ‘...
Supervisor: Assoc Professor Meredith O'Keeffe
Recently, novel genetic variants of GPR75 were discovered to be associated with leanness in large genome wide associated studies. This is the first...
Supervisor: Professor Zane Andrews
This study investigates the role of Smad3 acetylation in the development and progression of organ/tissue fibrosis.
Supervisor: Assoc Professor Jinhua Li
Small noncoding RNAs are increasingly recognised as important regulators of gene expression and genome integrity across all kingdoms of life. This is...
Supervisor: Dr Peter Boag
The tyrosine kinase Src was the first proto-oncogene to be identified, and it is now known that Src plays an important role in several human cancers...
Supervisor: Professor Roger Daly
Dysfunctional feeding behaviour encompasses energy overconsumption (obesity, binge eating) to malnutrition (unhealthy food choices, excessive dieting...
Supervisor: Professor Zane Andrews
We are performing in-depth characterization of the microenvironment of human tumours, and discovering new mechanisms used by these cells to influence...
Supervisor: Dr Anne Fletcher
The oocyte-secreted TGF-beta proteins, BMP15 and GDF9, are essential for the acquisition of oocyte developmental competence during folliculogenesis....
Supervisor: Assoc Professor Craig Harrison
The oocyte-secreted factors, bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9), are essential for the acquisition of...
Supervisor: Dr Kelly Walton
The thymus is primarily responsible for generating naïve, self-tolerant T cells from hematopoietic precursors. However, deterioration of thymic...
Supervisor: Assoc Professor Ann Chidgey
Single cell technologies are being rapidly adopted and accordingly, there is a high demand for intuitive tools and software that help with the...
Supervisor: Professor Nicholas Huntington
Natural killer (NK) cells are effector lymphocytes of the innate immune system that are known for their ability to kill transformed and virus-...
Supervisor: Professor Nicholas Huntington