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Research Projects

Bariatric surgery has now been accepted as a front-line treatment for type 2 diabetes (T2D) that compares favourably with lifestyle and medicinal...

Obesity is a major public health burden worldwide, where 2/3 Australians are overweight and/or obese. Obesity greatly increases the risk of diabetes...
Supervisor: Dr Denuja Karunakaran

DC monitor the environment for potential “danger signals” that signify pathogen invasion, including non-homeostatic cell death caused by viruses. We...

Thin, flat, branched actin cytoskeleton filled membrane protrusions like the lamellipodia and membrane ruffles are utilized by cells for a plethora...
Supervisor: Dr Senthil Arumugam

The shape of the lower jaw (mandible) and dentition in non-human primates varies between species but the reasons behind this morphological variation...

The presentation of post-translationally modified (PTM) peptides by cell surface MHC molecules increases the diversity of targets for recognition by...
Supervisor: Dr Nathan Croft

Malaria is one of the most devastating infectious diseases worldwide, causing major public health, social and economic problems globally. The lack of...

It is well-established that neurons in the whisker area of somatosensory cortex and thalamus exhibit directional selectivity. Direction preference is...
Supervisor: Dr Mehdi Adibi

Our mothers programed the first decisions of our lives by mRNA dumping: the regulated translation of this maternal transcriptome controls the first...
Supervisor: Prof Traude Beilharz

Monoclonal antibodies (mAbs) that block checkpoint inhibitory receptors including Programmed Death (PD)-1 act directly on T cells to overcome ‘...

Recently, novel genetic variants of GPR75 were discovered to be associated with leanness in large genome wide associated studies. This is the first...

This study investigates the role of Smad3 acetylation in the development and progression of organ/tissue fibrosis.

Small noncoding RNAs are increasingly recognised as important regulators of gene expression and genome integrity across all kingdoms of life. This is...
Supervisor: Dr Peter Boag

The tyrosine kinase Src was the first proto-oncogene to be identified, and it is now known that Src plays an important role in several human cancers...
Supervisor: Professor Roger Daly

Dysfunctional feeding behaviour encompasses energy overconsumption (obesity, binge eating) to malnutrition (unhealthy food choices, excessive dieting...

Heme is an essential nutrient for the bacterial pathogen Haemophilus influenzae, which causes serious respiratory infections, otitis media and...
Supervisor: Dr Rhys Grinter

We are performing in-depth characterization of the microenvironment of human tumours, and discovering new mechanisms used by these cells to influence...
Supervisor: Dr Anne Fletcher

Development of therapeutic antibodies to treat human diseases

The oocyte-secreted TGF-beta proteins, BMP15 and GDF9, are essential for the acquisition of oocyte developmental competence during folliculogenesis....

The oocyte-secreted factors, bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9), are essential for the acquisition of...
Supervisor: Dr Kelly Walton

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