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Research Projects

The immune system comprises a variety of effector cells that are uniquely poised to recognize infected or transformed cells. However, the capacity of...
Supervisor: Dr Richard Berry

Viruses and pathogens are part of day-to-day encounters that the immune system needs to deal with. How the immune system “sees”, recognises and...

Perforin and the Complement Membrane Attack Complex (MAC) are related pore forming immune effectors that are deployed by the immune system to...

In this project, in collaboration with Professor Ross Hannan (ANU), we will study the structure of Upstream Binding Factor (UBF) in complex with...

SAGA’s many functions are essential for normal embryo development in flies and mice. Mutation or altered expression of SAGA subunits are associated...
Supervisor: Dr Hans Elmlund

Nanocomposite biomaterials are an emerging area of research as we seek to optimise the properties of biomaterials to enhance their suitability for...
Supervisor: Dr Mark Del Borgo

Like many developed countries, the population of Australia is ageing; with 13.8% of the population currently over the age of 65 and predictions this...

Post-translational modification of joint proteins leads to the generation of autoantigenic peptides that drive the inflammatory response in...
Supervisor: Dr Hugh Reid

Neurogenesis describes the fundamental process of generating neurons that integrate into existing circuits. Although originally thought to cease...

Cancer cachexia is a life-threatening condition characterised by a progressive loss of skeletal muscle and fat mass. Up to 80% of patients with...

Atherosclerosis, the process by which fats, cholesterol and other substances build up in the artery wall, is the leading cause of CV disease. This...
Supervisor: Dr Kristen Bubb

The global threat from antimicrobial resistance (AMR) was highlighted by the World Health Organization in its first-ever priority pathogen list of...
Supervisor: Dr Meiling Han

This study is focused on understanding the of the role of gut microbial metabolites on the mitochondria function and how may affect immune-metabolic...

This project aims to develop novel antisense oligonucleotides as an efficient and common therapeutic for targeting the polymyxin resistant gram-...
Supervisor: Dr Nitin Patil

The transcript encoding the proto-oncogene MYC is commonly overexpressed in prostate cancer (PC). MYC protein abundance is also increased in the...
Supervisor: Dr Luc Furic

Hypertension is a major cause of heart failure, heart attacks and strokes. Associated with the development of hypertension is the accumulation of...

Pulmonary hypertension (PH) is an incurable disease and a major cause of death and illness throughout the world. Whilst there has been advancement...

Background: Strong climatic changes may have been the primary drivers of human evolution. Understanding how early human (hominin) foraging and...
Supervisor: A/Prof Luca Fiorenza

The Lappan Group in the Department of Microbiology at Monash University is seeking a PhD student with a keen interest in microbial ecology or...
Supervisor: Dr Rachael Lappan

In celiac disease (CD), the T cell response to gliadin peptides derived from gluten in from wheat, barley and rye has been well characterised....
Supervisor: Dr Hugh Reid

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