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Research Projects

Plasmin (Plm) plays a crucial role in blood clot dissolution (fibrinolysis), inflammation, cellular migration and wound healing. Alpha2-antiplasmin (...
Supervisor: Dr Ruby Law

Natural killer (NK) cells are the founding members of the innate lymphoid cell family and contribute to the rapid production of inflammatory...

The mammalian oocyte is the largest cell in the body and undergoes two highly specialised asymmetric meiotic cell divisions. Coordination of...

The Bcl-2 family of proteins is crucial for apoptosis (a form of programmed cell death) regulation. The Bcl-2 proteins are synthesized in cytosolic...

Hypertension and its associated complications affect men and women during different stages of their lives. Our research is focusing on what controls...
Supervisor: Dr Katrina Colafella

Inflammation is the body’s response to injury or infection. A key feature of inflamed tissues is the accumulation of leukocytes (white blood cells),...

Obesity and overweight are major health concerns and a burden to public health in Australia, affecting 2 in 3 adults (12.5 million), and 1 in 4...

Spontaneous synchronization is a common phenomenon occurring in diverse contexts, from a group of glowing fireflies or chirping crickets in a field...
Supervisor: Dr Mehdi Adibi

We have identified specific sphingolipids that control brain development and protect the nervous system throughout life. This exciting project will...

The Combes laboratory has opportunities for postgraduate research projects in animal and stem cell models of kidney development and disease, advanced...
Supervisor: Dr Alex Combes

The prevalence of diabetes mellitus continues to increase worldwide leading to premature mortality. About 30% of patients with type 2 diabetes (T2D)...

This project examines how weight gain is affected by stress and the bidirectional relationship between mind and body in stress, metabolism, comfort...
Supervisor: Dr Kevin Lee

Eukaryotic transcriptional co-activators are multi-subunit complexes that both modify chromatin and recognize histone modifications to control gene...
Supervisor: Dr Dominika Elmlund

The immune system comprises a variety of effector cells that are uniquely poised to recognize infected or transformed cells. However, the capacity of...
Supervisor: Dr Richard Berry

Viruses and pathogens are part of day-to-day encounters that the immune system needs to deal with. How the immune system “sees”, recognises and...

Perforin and the Complement Membrane Attack Complex (MAC) are related pore forming immune effectors that are deployed by the immune system to...

In this project, in collaboration with Professor Ross Hannan (ANU), we will study the structure of Upstream Binding Factor (UBF) in complex with...

SAGA’s many functions are essential for normal embryo development in flies and mice. Mutation or altered expression of SAGA subunits are associated...
Supervisor: Dr Hans Elmlund

Nanocomposite biomaterials are an emerging area of research as we seek to optimise the properties of biomaterials to enhance their suitability for...
Supervisor: Dr Mark Del Borgo

Like many developed countries, the population of Australia is ageing; with 13.8% of the population currently over the age of 65 and predictions this...

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