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Research Projects

Pleurotolysin: a pore forming toxin from the carnivorous oyster mushroom

Putting the brakes on inflammation: Using the structure of important immune protein receptors to develop therapeutics

The sheer mechanical power of shark jaws, combined with an increase in shark bites in Australia since the 2000s, have accelerated the need for the...

Over the past years, our scientific and clinical research team has pursued basic discovery and preclinical research into the skin autoimmune disease...
Supervisor: Dr. Asolina Braun

Gamma-aminobutyric acid (GABA) produced by Glutamic Acid Descarboxylase (GAD) is the most abundant neurotransmitter inhibitor in the CNS and is...

The laboratory is interested in the transcriptional and epigenetic mechanisms that govern cell identity, in particular pluripotency and the...

Here we will combine omics technologies with novel muscle-specific gene manipulation technologies to discover novel signalling pathways controlling...
Supervisor: Dr Adam Rose

Plasmin (Plm) plays a crucial role in blood clot dissolution (fibrinolysis), inflammation, cellular migration and wound healing. Alpha2-antiplasmin (...
Supervisor: Dr Ruby Law

Natural killer (NK) cells are the founding members of the innate lymphoid cell family and contribute to the rapid production of inflammatory...

The mammalian oocyte is the largest cell in the body and undergoes two highly specialised asymmetric meiotic cell divisions. Coordination of...

The Bcl-2 family of proteins is crucial for apoptosis (a form of programmed cell death) regulation. The Bcl-2 proteins are synthesized in cytosolic...

Hypertension and its associated complications affect men and women during different stages of their lives. Our research is focusing on what controls...
Supervisor: Dr Katrina Colafella

Inflammation is the body’s response to injury or infection. A key feature of inflamed tissues is the accumulation of leukocytes (white blood cells),...

Obesity and overweight are major health concerns and a burden to public health in Australia, affecting 2 in 3 adults (12.5 million), and 1 in 4...

Spontaneous synchronization is a common phenomenon occurring in diverse contexts, from a group of glowing fireflies or chirping crickets in a field...
Supervisor: Dr Mehdi Adibi

We have identified specific sphingolipids that control brain development and protect the nervous system throughout life. This exciting project will...

The Combes laboratory has opportunities for postgraduate research projects in animal and stem cell models of kidney development and disease, advanced...
Supervisor: Dr Alex Combes

The prevalence of diabetes mellitus continues to increase worldwide leading to premature mortality. About 30% of patients with type 2 diabetes (T2D)...

This project examines how weight gain is affected by stress and the bidirectional relationship between mind and body in stress, metabolism, comfort...
Supervisor: Dr Kevin Lee

Eukaryotic transcriptional co-activators are multi-subunit complexes that both modify chromatin and recognize histone modifications to control gene...
Supervisor: Dr Dominika Elmlund

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