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Research Projects

People usually begin to lose some degree of height around the age of 40 and their rate of decline in height tends to increase with age. Such height...
Supervisor: Aung Zaw Zaw Phyo

The problem: Picture this… Cheng is an 83-year-old woman living with dementia in a residential aged care facility (RACF), she has frequent falls....

The currently identified genetic prostate cancer risk factors account for less than 40% of the familial risk for the disease. Very few of these...

Known genetic risk factors for prostate cancer include rare genetic variants in prostate cancer predisposition genes that are associated with high to...

For over 100 years the need to understand particular disease causing, bacterial isolates to treat disease has been clearly understood. Importantly,...

Epilepsy is a severe neurological disorder characterized by recurrent seizures that affect 1% of the population worldwide. Traumatic brain injury (...

The ankle is a clinically important weight-bearing joint, and damage at this site is relevant to osteoarthritis, post-traumatic joint disease, and...

RASopathies that are caused by germ-line mutations affecting genes residing along the canonical MAPKinase signaling pathway. They constitute the...
Supervisor: Fabrice Jaffré

hiPSC technology coupled with genome editing technology (CRISPR) offers an unprecedented opportunity to study patient-specific disease in a dish....
Supervisor: Fabrice Jaffré

In collaboration with a Maternal-Fetal Medicine colleague from the United States who has been working on the role of Human Leukocyte Antigens (HLA)...
Supervisor: Daniel Rolnik

The MACPF/CDC family proteins use a common fold to oligomerise into a ring-shaped transmembrane pore capable of either direct cell lysis or passive...

Contemporary treatment of multiple myeloma and acute lymphoblastic leukaemia (ALL) still relies heavily on steroids (glucocorticoids - like...
Supervisor: Professor Jake Shortt

This study examines the mental health outcomes for people who are treated in a novel, post-suicide attempt outreach program. The program is one of...

Hospital admissions can expose older adults to a spectrum of avoidable and costly harms. Not least of these is hospital-associated functional decline...

Immunity to malaria is slow to develop due to the rapid induction of regulatory cell responses that hamper adaptive immunity. Type I IFN signalling...
Supervisor: A/Prof Michelle Boyle

The strongest predictor of experiencing a severe COPD exacerbation (flare-up) requiring hospital admission is having had a severe exacerbation in the...

Male and female brains differ in anatomy and chemistry The prevailing dogma that oestrogen is the key factor involved in brain sex differentiation...

This study will be undertaken in collaboration with health care providers in palliative care and addiction services. The palliative care of people...
Supervisor: Ms Katrina Recoche

Injury creates a fertile environment allowing for plasticity mechanisms to shape recovery. The ability of the brain to reorganize synaptic...
Supervisor: Dr Nafiseh Atapour

Skeletal muscle is the largest tissue by mass in the human body and yet there is a major clinical gap in the lack of treatments for diseased muscle....
Supervisor: Meagan McGrath

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