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Research Projects

Vaccines exploit the ability of the immune system to provide heightened, tailored responses to pathogens if the host has been infected prior – this...

We are interested in delineating the molecular pathways that control immune cell function during infection and inflammation. Our group is focused on...
Supervisor: Professor Colby Zaph

The innate immune system is the body’s first line of defence against infection, and is necessary for our survival. Our cells have evolved specialized...

This project aims to better define rates of reactivation from the point of initial exposure/infection to the later development of active TB. The...
Supervisor: A/Prof James Trauer

A sudden worsening of respiratory symptoms in Chronic obstructive Pulmonary Disease (COPD) is called a flare up. These flare ups are caused by...
Supervisor: Dr Arwel Jones

Plasmid transmission between bacteria of the same or different species is an important driver of genetic diversity, bacterial adaptation and...
Supervisor: Dr Margaret Lam

Polysaccharide capsule is a critical virulence factor in many bacteria, including the priority drug-resistant pathogen Acinetobacter baumannii. The...
Supervisor: Dr Francesca Short

The COVID19 pandemic has highlighted the vulnerability of older individuals to suffer more severe disease outcomes from infectious respiratory...
Supervisor: Dr Anna Hearps

Exosomes are small vesicles (50-150 nm in size) secreted by most cell types and are involved in cell - cell communication and regulation of immune...
Supervisor: Professor Brian Cooke

The Lieschke group studies the haemopoietic system and leukocytes. The haemopoietic system is a collection of organs and tissues (bone marrow,...

Klebsiella pneumoniae is a major cause of antibiotic resistant hospital-associated infections that can be extremely difficult to treat. The World...
Supervisor: Dr Kelly Wyres

The treatment of bacterial infections in humans and animals has largely relied on the use of antibiotics for over 70 years. One consequence of the...
Supervisor: Professor Dena Lyras

Antibody development in response to infection and vaccination in humans is poorly understood, in part due to the difficult in accessing secondary...
Supervisor: A/Prof Michelle Boyle

The importance of hospital admissions data to inform health policy has been evident over the past few years, with the pressure that the COVID-19...
Supervisor: Dr Daniel Griffiths

The eukaryotic genome consists of two classes of genes preceded by distinctly different promoter sequences. Housekeeping genes (90%) code for...
Supervisor: Dr Hans Elmlund

Gastric cancer is a leading cause of cancer-related death, claiming more than 1 million lives annually. A major predisposing factor to developing...
Supervisor: Dr Dustin Flanagan

Plasma cells (PC) are the only cell type secreting antibodies, which are important for protective immunity to fight against pathogens. However,...
Supervisor: Dr Zhoujie (Zoe) Ding

Group A Streptococcus hijacks host plasminogen to facilitate colonization and dissemination. This infection can lead to life-threatening infections...
Supervisor: Dr Ruby Law

To be able to stave off infections and cancers throughout life, our immune systems first need to recognise and tolerate the ~200 different cell types...
Supervisor: Dr Stephen Daley

The adaptive arm of immune system uses lymphocytes to generate antibody and memory responses to challenges throughout life. Three lineages of...
Supervisor: Dr Martin Davey

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