Research Projects
Conventional chemotherapeutic agent, temozolomide (TMZ), for Glioblastoma (GBM) often displays high chemoresistance with various side effects....
Supervisor: Alfarizal Kamarudin
Surface polysaccharides are common antigens in priority bacterial pathogens and therefore attractive targets for novel control strategies such as...
Supervisor: Dr Tom Stanton
We wish to understand the detailed molecular events that underlie the recruitment and regulation of chromatin-modifying complexes by their co‐factor...
Supervisor: Assoc Professor Chen Davidovich
The Functional Annotation of Tumor Variants of Unknown Significance (VUS) using CRISPR project aims to elucidate the functional significance of...
Supervisor: Dr Claire Sun
Gastric cancer (GC) is the fourth most common cancer globally. It has defined premalignant stages and progresses through Intestinal Metaplasia (IM)...
Supervisor: Professor Alex Boussioutas
Genetic variants (DNA changes) can result in increased risk of diseases like cancer, cardiovascular disease and dementia. However, some DNA changes...
Supervisor: Professor Paul Lacaze
Klebsiella pneumoniae is a major cause of antibiotic resistant hospital-associated infections that can be extremely difficult to treat. The World...
Supervisor: Assoc/Prof Kelly Wyres
Antimicrobial resistance (AMR) is a key global issue, with resistance to important antibiotics increasing yearly, resulting in 1.14 million deaths in...
Supervisor: Dr Margaret Lam
Invasive lobular breast cancer is a specific histological type of breast cancer that makes up about 10% of all invasive breast cancer diagnoses. It...
Supervisor: Professor Melissa Southey
Antigen presentation is the fundamental and complex process in which a cell breaks down proteins into small fragments (peptides) and presents these...
Supervisor: Chen Li
The human genome is dominated by non-protein encoding information. Indeed, the differences between humans and other animals cannot be accounted for...
Supervisor: Prof Traude Beilharz
The currently identified genetic prostate cancer risk factors account for less than 40% of the familial risk for the disease. Very few of these...
Supervisor: Professor Melissa Southey
Known genetic risk factors for prostate cancer include rare genetic variants in prostate cancer predisposition genes that are associated with high to...
Supervisor: Professor Melissa Southey
For over 100 years the need to understand particular disease causing, bacterial isolates to treat disease has been clearly understood. Importantly,...
Supervisor: Assoc Prof Sam Forster
Epilepsy is a severe neurological disorder characterized by recurrent seizures that affect 1% of the population worldwide. Traumatic brain injury (...
Supervisor: A/Prof Pablo Casillas-Espinosa MD, PhD
Plasma cells (PC) are the only cell type secreting antibodies, which are important for protective immunity to fight against pathogens. However,...
Supervisor: Dr Zhoujie (Zoe) Ding
Sarcomas are a rare type of cancer that originate in the connective tissue of the body, including fat, muscle, bone, and cartilage. Sarcoma’s can...
Supervisor: A/Prof Jason Cain
Clozapine is one of the multi-target drugs that remains the only approved treatment for treatment-resistant schizophrenia. The multi-target nature of...
Supervisor: Dr Sathish Periyasamy
Project Overview:
In the ever-evolving landscape of medical research, the pursuit of innovative solutions to combat cancer and autoimmune diseases...
Supervisor: Dr Pouya Faridi
From early in life we are exposed to trillions of microbes and food proteins through our intestines, and only occassionally are the microbes...
Supervisor: Dr Marcus Robinson