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Research Projects

The JAK-STAT signalling pathway is critical for propagation of signals from the engagement of cytokines with receptors on the surface of blood cells...

Erythroleukaemia is a relatively rare type of acute myeloid leukaemia. The genetics which underpin the disease have recently been discovered in large...

Adult haematopoietic stem cells (HSCs) first develop in the early embryo from endothelial cells in the wall of the dorsal aorta in response to shear...

DNA methylation is a key mechanism by which gene expression is regulated. Mutations in DNA methylation enzymes such as DNMT3A, TET2 and IDH1 and 2...