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hiPSC-derived cardioids to study the impact of RASopathy mutations on human cardiogenesis
RASopathies that are caused by germ-line mutations affecting genes residing along the canonical MAPKinase signaling pathway. They constitute the...
Supervisor: Fabrice Jaffré
hiPSC-derived engineered heart tissue to study the impact of novel hypertrophic cardiomyopathy-associated MYBPC3 variants
hiPSC technology coupled with genome editing technology (CRISPR) offers an unprecedented opportunity to study patient-specific disease in a dish....
Supervisor: Fabrice Jaffré
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