Research Projects
Acute myeloid leukaemia (AML) is caused by accumulated oncogenic mutations in white blood cell progenitors that lock them into an immature self-...
Supervisor: Assoc Professor Ross Dickins
Clonal haematopoiesis of indeterminate potential (CHIP) is defined as the presence of blood cancer-associated mutations without evidence of...
Supervisor: Professor David Curtis
Generating mouse models of clonal hematopoiesis to study the potential of apsirin to prevent cancers
Clonal haematopoiesis of indeterminate potential (CHIP), defined as the presence of blood cancer-associated mutations with a variant allele frequency...
Supervisor: Professor David Curtis
Type one diabetes (T1D) has reached epidemic proportions and people living with the disease are dependent on insulin therapy to help keep their blood...
Supervisor: Prof Christoph Hagemeyer
The acquisition of resistance to therapies by cancer cells, sadly, is often inevitable. To effectively treat cancer, we need to understand how...
Supervisor: Dr Omer Gilan
In 2006, Shinya Yamanaka and colleagues made the groundbreaking discovery that differentiated cells can be reprogrammed back to a pluripotent state...
Supervisor: Assoc Professor Matthew McCormack
Self-reactive T cells cause many autoimmune diseases, and can also trigger serious autoimmune side-effects in cancer patients undergoing...
Supervisor: Assoc Professor Ross Dickins
This project is based on the single-chain antibody (scFv) technology, an emerging class of biotechnologically produced therapeutics. ScFvs are...
Supervisor: Prof Christoph Hagemeyer
This project aims to develop nanoparticle contrast agents for magnetic resonance imaging (MRI) that selectively target molecular markers of...
Supervisor: Prof Christoph Hagemeyer
Single-chain antibodies against epitopes associated with vascular dysfunction / injury provide a unique tool for specific targeting of exosomes in...
Supervisor: Prof Christoph Hagemeyer
Leukaemia stem cells are thought to be the source of relapse following treatment with conventional therapies. New and emerging treatments are better...
Supervisor: Dr Omer Gilan