Research Projects
The human genome is dominated by non-protein encoding information. Indeed, the differences between humans and other animals cannot be accounted for...
Supervisor: A/Prof Traude Beilharz
Small cell lung cancer (SCLC) is an incredibly aggressive form of lung cancer with limited treatment options, begging the need for major
therapeutic...
Supervisor: Professor Nicholas Huntington
Our group focuses of studying dendritic cells (DC) by analysing the cell surface receptors they express with the view that these receptors contribute...
Supervisor: Assoc Professor Irene Caminschi
The MACPF/CDC family proteins use a common fold to oligomerise into a ring-shaped transmembrane pore capable of either direct cell lysis or passive...
Supervisor: Assoc Professor Michelle Dunstone
The eukaryotic genome consists of two classes of genes preceded by distinctly different promoter sequences. Housekeeping genes (90%) code for...
Supervisor: Dr Hans Elmlund
Gastric cancer is a leading cause of cancer-related death, claiming more than 1 million lives annually. A major predisposing factor to developing...
Supervisor: Dr Dustin Flanagan
Developing tumour cells interact with a complex and heterogeneous ecosystem, namely the tumour microenvironment (TME), comprising mutant and wild-...
Supervisor: Dr Dustin Flanagan
To be able to stave off infections and cancers throughout life, our immune systems first need to recognise and tolerate the ~200 different cell types...
Supervisor: Dr Stephen Daley
Cancer cells can acquire stromal or developmental-like phenotypes allowing them to masquerade as other cell types, making the challenge of...
Supervisor: Dr Dustin Flanagan
The adaptive arm of immune system uses lymphocytes to generate antibody and memory responses to challenges throughout life. Three lineages of...
Supervisor: Dr Martin Davey
The adaptive arm of immune system uses lymphocytes to generate antibody and memory responses to challenges throughout life. Three lineages of...
Supervisor: Dr Martin Davey
The food intake of the mother during gestation and the breastfeeding period has far-reaching consequences for the development of the child and their...
Supervisor: Dr. Asolina Braun
People with underlying non-communicable disease have lower tolerance and worse outcomes to infections but we don't understand why. To begin to...
Supervisor: Dr Adam Rose
Studies in T cell mediated immunity have focused on understanding the presentation of peptides by the Major Histocompatibility Complex (MHC), and...
Supervisor: Dr Jerome Le Nours
Mitochondria are key players in health and disease. They are the main source of energy in eukaryotic cells, oxidizing sugars and fats to generate ATP...
Supervisor: Professor Mike Ryan
The academic research program within this laboratory is focused on defining the key molecular interactions underlying receptor recognition events...
Supervisor: Professor Jamie Rossjohn
Background:
The innate immune system senses and responds to endogenous and exogenous danger signals in order to protect the host. cGAMP synthase (...
Supervisor: Dr Dominic De Nardo
The academic research program within this laboratory is focused on defining the key molecular interactions underlying receptor recognition events...
Supervisor: Professor Jamie Rossjohn
Cytomegaloviruses (CMV) are a family of species-specific viruses that have evolved sophisticated strategies to interfere with host immunity, thereby...
Supervisor: Dr Richard Berry
The academic research program within this laboratory is focused on defining the key molecular interactions underlying receptor recognition events...
Supervisor: Professor Jamie Rossjohn