Research Projects
Project Aims: Identify genetic markers that predict the risk of valproate-induced birth defects.
It is recognised that women with epilepsy who...
Supervisor: Professor Terence O'Brien
Gliomas are the most common type of intrinsic brain tumour and a major cause of morbidity and mortality for those afflicted by these highly invasive...
Supervisor: Dr Mastura Monif
Acute myeloid leukaemia (AML) is caused by accumulated oncogenic mutations in white blood cell progenitors that lock them into an immature self-...
Supervisor: Assoc Professor Ross Dickins
The burgeoning pandemic of antimicrobial resistant (AMR) bacterial pathogens poses a major threat to global health. In Australia alone, 6.5 deaths...
Supervisor: Dr Jane Hawkey
Alternative splicing is a regulatory pathway that can can change the messenger RNA produced from a gene and subsequently the proteins that are...
Supervisor: Professor Merlin Thomas
The pathophysiologic progression to heart failure is a complex process. Initial insults such a myocardial infarction or chronic hypertension, trigger...
Supervisor: Assoc Professor Bing Wang
COVID-19 vaccines are highly effective at preventing infection and severe disease from SARS-CoV-2. Although vaccination elicits neutralising...
Supervisor: Dr Paul Gill
Pulmonary rehabilitation is a core component of the therapeutic management of people chronic respiratory disease. A program of exercise and education...
Supervisor: Dr Narelle Cox
**New Projects On Offer for 2025**
Kabuki syndrome (KS) is a genetically heterogenous disorder characterised by striking facial features and multi...
Supervisor: Professor Sam El-Osta
The objective of this project is to gain a deeper understanding of the regulation of glyoxalase (GLO1), an enzyme that plays a crucial role in...
Supervisor: Dr Carlos Rosado
For cells to function and therefore life to exist, proteins have to be processed and their constituents recycled or destroyed. The Proteasome is the...
Supervisor: A/Prof Vivek Naranbhai
A biomarker is an objectively measured characteristic of a normal or pathologic biological process. The development of novel interventions to treat,...
Supervisor: Dr Pablo Casillas-Espinosa MD, PhD
Intimate partner violence (IPV) is a serious problem that affects one in six women in Australia, and it is the leading cause of preventable death,...
Supervisor: Dr Georgia Symons
Organism-specific interpretation of antimicrobial susceptibility testing (AST) data is standard in clinical microbiology, with rules regularly...
Supervisor: Dr Jane Hawkey
Heart failure (HF) with preserved ejection fraction (HFpEF) is increasing in prevalence and is associated with high morbidity and mortality. The...
Supervisor: Assoc Professor Bing Wang
Status epilepticus (SE), characterised by prolonged or repeated seizures with incomplete recovery, is a critical neurological emergency associated...
Supervisor: Dr Janine Liu
Need for a novel solution.
Despite advances in the treatment of atherosclerotic cardiovascular disease (CVD), the risk of CVD remains higher in...
Supervisor: Dr Waheed Khan
Background:
Over 400,000 Australians are affected by diabetic kidney disease. Current clinical therapies only delay the progression to end stage...
Supervisor: Assoc Professor Melinda Coughlan
This project seeks to comprehensively characterize our prototype inhibitor of CDA1, CHA-061, for its treatment effect on diabetes associated kidney...
Supervisor: Dr Zhong-Lin Chai
This project seeks to comprehensively characterize our prototype inhibitor of CDA1, CHA-061, for its treatment effect on diabetes associated kidney...
Supervisor: Dr Zhong-Lin Chai