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Research Projects

Human challenge trials are research trials in which participants are intentionally challenged (whether or not they have been vaccinated) with an...
Supervisor: Dr Arwel Jones

We have established a large cohort of patients with predominantly antibody deficiency (PAD), the most prevalent symptomatic form of primary...

Immunology and Human Pathology are dynamic disciplines, with many inter-disciplinary alignments --in content, techniques and toolboxes. Face-to-face...
Supervisor: Dr Jessica Borger

Depression and anxiety are common, debilitating and chronic mental health conditions which can be difficult to effectively treat. We aim here to...

Project Aims: Identify genetic markers that predict the risk of valproate-induced birth defects. It is recognised that women with epilepsy who...

Heart failure occurs when the heart muscle weakens and is unable to pump enough blood to meet the body’s needs. It is a major public health issue,...
Supervisor: Dr Morag Young

Postural Orthostatic Tachycardia Syndrome (POTS) is a condition of chronic orthostatic intolerance for which the hallmark is an excessive increase in...
Supervisor: Professor Sam El-Osta

It is well-known that preoperative cytological assessment for thyroid nodules can be improved in those patients with an indeterminate cytology, and...
Supervisor: A/Prof. James Lee

Alzheimer's disease (AD) patients are 10 times more likely to develop epilepsy compared with age-matched controls. The treatment of recurrent...

Gliomas are the most common type of intrinsic brain tumour and a major cause of morbidity and mortality for those afflicted by these highly invasive...
Supervisor: Dr Mastura Monif

Acute thrombosis causes vessel occlusion resulting in ischemic complications, such as myocardial infarction and stroke, and is a major cause of death...
Supervisor: Dr Xiaowei Wang

Acute myeloid leukaemia (AML) is caused by accumulated oncogenic mutations in white blood cell progenitors that lock them into an immature self-...

Magnetic Resonance Imaging (MRI) represents the gold standard for radiological diagnosis and monitoring of neurological diseases such as multiple...
Supervisor: Dr Scott Kolbe

In Australia hepatitis C infection predominately infects people who inject drugs. Direct acting antiviral therapy can cure the infection in around...

The JAK-STAT signalling pathway is critical for propagation of signals from the engagement of cytokines with receptors on the surface of blood cells...

This annual cross-sectional survey is run every year at Melbourne Sexual Health Centre through our computer-assisted self-interview (CASI) that all...
Supervisor: Dr Tiffany Phillips

The pathophysiologic progression to heart failure is a complex process. Initial insults such a myocardial infarction or chronic hypertension, trigger...

It has become increasingly clear that immune cells can change their metabolic state in response to activation in order to meet their energy...

Multiple sclerosis, an autoimmune, neurodegenerative condition, is the most common cause of non-traumatic neurological disability in young adults....
Supervisor: Dr Vilija Jokubaitis

Post-traumatic epilepsy (PTE) is a recurrent seizure disorder due to brain injury following physical trauma. PTE accounts for 20% of symptomatic...
Supervisor: Miss Rui Li

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