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Whole genomic sequencing analysis of genetic and acquired rat strains

Description 
Whole genome sequence data is available for the GAERS epilepsy rat model of idiopathic generalised epilepsy (IGE), and its sibling strain the NEC non-epileptic rat, as well as a rat model of vulnerability to acquired epilepsy (FAST) and a resistant rat strain (SLOW). This project will explore the whole genomes of these strains to identify potential genetic aberration markers of epilepsy, and the vulnerability to develop epilepsy after a brain injury. This project will require interest in genetics, bioinformatics and big data.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
epilepsy, animal models, whole genome sequencing, genomics, physiology, pharmacology, microbiology, anatomy, developmental biology, molecular biology, biochemistry, immunology, human pathology, clinical, neuroscience
School 
Central Clinical School » Neuroscience
Available options 
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Graduate Diploma
Short projects
Time commitment 
Full-time
Part-time
Top-up scholarship funding available 
Yes
Year 1: 
$30000
Physical location 
Alfred Research Alliance
Co-supervisors 
Dr 
Pablo Casillas-Espinosa
Dr 
Bridgette Semple

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