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Understanding the neuroimmune axis during neuroinflammation

Description 
Our brains are predominantly made up of neurons responsible for transmitting signals, but also specialised immune cells called microglia that help protect and support them. This neuroimmune axis maintains neuronal balance and facilitates repair, but when dysregulated, drives neuroinflammation linked to many brain disorders. We aim to understand the interaction between neurons and microglia during inflammatory events in the brain, and whether modulation of microglia activity protects neuronal function. Histological immunofluorescent analysis of brain tissue, combined with in vivo intravital microscopy, and behavioural analysis will unravel this poorly understood relationship.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Neuroinflammation, inflammation, neurological, immune, microglia, immunology, microscopy, histology
School 
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research » Medicine - Monash Medical Centre
Available options 
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Monash Medical Centre Clayton
Co-supervisors 
Prof 
Connie Wong

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