Uncovering molecules associated with healthy ageing and exercise responses

This project aims to uncover sex-specific molecular marks that either predict or mediate healthy ageing and exercise responses in muscle. The following techniques will be utilised: Human exercise trials to measure fitness outcomes (VO2 max and strength) and molecular outcomes via analysis of blood and muscle samples. Techniques used for molecular analysis include muscle cross-sectional area and fibre type using immuno-histochemistry, preparation and analysis of ‘omics’ datasets including methylation, transcriptomics and proteomics. In addition, we use Bioinformatics techniques for data analyses.