Stroke associated with medium vessel occlusion

Ischaemic stroke results from occlusion of the cerebral circulation. Clot removal has been shown to be effective in reducing disability associated with large vessel occlusion. The optimal management of clot resulting from medium vessel occlusion is still unclear. It is uncertain if clot removal or clot busting drug is the best treatment. There are several trials evaluating this treatment including the Frontier AP trial. This trial has received funding from NHMRC Clinical Trial Cohort Grant ID 2032420. The project available is suitable for neurology/geriatrician/rehabilitation trainee or specialist wishing to undertake PhD study. This will involve learning multivariate methods to relate anatomical location of infarct to stroke deficit and disability. Examples of related material can be found at https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.00773/full and https://www.ahajournals.org/doi/abs/10.1161/STROKEAHA.123.046083 The project can be tailor made depending on the medical specialty interest of the candidate. One angle can be post-stroke cognitive dysfunction, post-stroke delirium, precision medicine approach to rehabilitation.