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The role of a novel cytokine in endometrial and cervical cancer

Description 
Cervical and endometrial cancers are major human diseases with unmet medical needs. We have recently discovered a new interferon designated interferon epsilon (IFNe) which is highly expressed constitutively in the female reproductive tract and regulated by hormones. IFNe belongs to a cytokine family which regulates the development of cancers by direct effects on cell proliferation, survival and migration as well as by indirect effects of activating innate and adaptive anti-tumour immunity. Aspects of this project will utilize preclinical models of these diseases, in vitro cell biology and molecular genetics approaches to examine the effects of IFNe in the development and/or therapy of endometrial and cervical cancers. Key words: Cancer, immunity, novel therapeutics, reproductive health, anti-tumour responses
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Cancer, immunity, novel therapeutics, reproductive health, anti-tumour response, ovarian cancer, tumour immunology, immunotherapy
School 
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research » Molecular and Translational Sciences
Available options 
PhD/Doctorate
Honours
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Monash Health Translation Precinct (Monash Medical Centre)
Co-supervisors 
Dr 
Nicole Campbell

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