New incontinence is a devastating and not uncommon consequence of stroke - affecting 30-40% of survivors. Rehabilitation of continence is poorly implemented in clinical practice and currently based upon behavioral therapies and patient education. Transcutaneous tibial nerve stimulation (TTNS) is a non-invasive therapy that stimulates the neural pathway responsible for continence. TTNS is hypothesized to contribute to long-term symptom improvement of post-stroke incontinence by modifying neural responses to signals related to continence functions. We hope to perform a small pilot study, testing the feasibility of TTNS in acute stroke patients with new bladder or bowel incontinence. The project would involve writing a comprehensive literature review on the topic and assisting with the administration of TTNS and recording patient related outcomes in study subjects - alongside co-supervisor Eric Cruz. Training regarding TTNS will be provided and for any other technical aspects of delivering the study. The supervisors will finalize the study protocol and obtain ethical approval prior to the start of the study. The project would suit anyone interested in neuroscience and clinical research and would give great exposure to conducting clinical research in a real world setting.
stroke, rehabilitation, nerve stimulation, continence, clinical trial, neuroscience
Central Clinical School