Description
How nutrients (e.g. amino acids) and hormones (e.g. glucagon) signal within the liver to control metabolism is far from fully understood. Here using cell based Crispr-Cas9 screens as well as proteomics/metabolomics we aim to discover novel signalling pathways downstream of hormones and nutrients controlling metabolic homeostasis. Whatever we discover has implications for basic metabolic biology as well as diseases such as cardiometabolic diseases (type 2 diabetes, atherosclerosis, fatty liver, kidney disease and cancer).
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
metabolism, signalling, cell biology, physiology, cancer, diabetes, Department of Biochemistry and Molecular Biology
School
Biomedicine Discovery Institute (School of Biomedical Sciences) » Biochemistry and Molecular Biology
Available options
PhD/Doctorate
Honours
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Clayton Campus
Research webpage