A novel approach in improving lipidomics throughput for population profiling

• Lipids are key biological molecules essential to life. Lipidomics is the characterisation and study of the complete lipidome of a biological system (fluid, cell, tissue, organism). In humans, plasma is an easy to obtain bio-fluid where lipids have been demonstrated to be perturbed in various disease settings. • Diseases can affect everyone differently, in order better understand the relationship between lipids and disease, larger population studies are needed. Clinically related studies in the field have been limited, owing to the limitations in the rate where plasma samples can be profiled in a comprehensive manner. This study aims to generate a novel approach in comprehensive lipidomic profiling using high resolution mass spectrometry approaches in conjunction with computational biology. Students should be technology/computation oriented.