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Mechanisms of Candida albicans infection in the kidney

Description 
Immunosuppressed individuals such as renal transplant recipients are at particular risk of systemic infection with the fungal pathogen, Candida albicans. One of the organs commonly targeted by C. albicans is the kidney. However, the mechanism whereby C. albicans invades the kidney, and the nature of the local inflammatory response following infection are poorly understood. The aim of this project will be to investigate these processes making use of our laboratory’s world-leading expertise in in vivo imaging of the kidney. State-of the-art approaches will be used for in vivo visualisation of C. albicans as well as resident and circulating immune cells in the kidney during the response to infection. In these experiments, skills will be developed in small animal surgery, in vivo multiphoton imaging, flow cytometry and other immunological techniques.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Kidney, infection, imaging, leukocyte
School 
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research
Available options 
PhD/Doctorate
Honours
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Monash Health Translation Precinct (Monash Medical Centre)

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