Acute kidney injury occurs in approximately 25% of patients who undergo cardiac surgery requiring cardiopulmonary bypass. During cardiopulmonary bypass, the roles of the heart and lungs are taken over by a machine. This renders the kidney susceptible to hypoxia, which in turn appears to be one of the factors that leads to development of acute kidney injury. To find ways to improve kidney oxygenation during cardiac surgery, we are using an experimental model in sheep to examine the effects of changing the perfusion conditions maintained by the heart-lung machine. This project would be partly based in the Department of Physiology and partly based at the Florey Institute of Neuroscience and Mental Health.
acute kidney injury, renal physiology, hypoxia, renal circulation, cardiac surgery, integrative physiology, department of physiology
Biomedicine Discovery Institute (School of Biomedical Sciences) » Physiology
Masters by research
Top-up scholarship funding available
Biomedicine Discovery Institute