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A first photochromic regulator of stem cell differentiation

Description 
Stem cells are pluripotent cells that can be differentiated into many different cell types and that harbour enourmous technological and medical potential. The overall goal of this project is to establish a new approach to regulate stem cell differentation using light as a synthetic signal. The group has recently developed a chemical molecule that acts as a potent differentiating agent of human stem cells but that, unlike any other known agent, can be reversibly (in-)activated by light. The specific aims of this project are to characterize this first photochromic regulator of stem cell differentiation and to apply it towards novel cell state and cell fate experiments. Please also refer to our website www.janovjak-lab.com for more information.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Stem cells, retinoic acid, optogenetics, optical control, pluripotency
School 
Australian Regenerative Medicine Institute (ARMI)
Available options 
PhD/Doctorate
Masters by research
Honours
Graduate Diploma
Time commitment 
Full-time
Part-time
Top-up scholarship funding available 
Yes
Year 1: 
$5000
Physical location 
15 Innovation Walk

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