This project will investigate the role and mechanism of the micro-RNA processing complex (SRSF3 OncomiR-1) in colorectal cancer. Experiemntal approaches will include biochemical, biophysical and structural biology methods to understand how SRSF3 interacts with Drosha and DGCR8 to process the OncomiR-1 RNA substrate. The outcome of this project will provide insights into how SRSF3-OncomiR1 complex contribute to the progression of colorectal cancer.
Cancer, biochemistry, structural biology
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research
Masters by research
Top-up scholarship funding available
Monash Health Translation Precinct (Monash Medical Centre)