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Creating a new generation of adjuvants for vaccine and cancer immunotherapy

Description 
Our laboratory has recently discovered that select Toll like receptor agonists could be modified to present novel adjuvant properties - with broad implications in vaccine development and cancer treatments. This project will advance our knowledge of the therapeutic applications of our discovery using cutting age disease models to study immune responses - with a combination of in vitro and ex vivo experiments. It has the potential to revolutionise adjuvants (for instance leading to less frequent vaccinations in children), and reignite immune responses against cancer cells within the tumor microenvironment. Importantly, the successful candidate is guaranteed to publish peer-reviewed works related to their studies upon joining our laboratory (with a possible Thesis by publication stream for PhD students).
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Innate immunity, adjuvants, immune responses, cancer immunotherapy
School 
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research » Molecular and Translational Sciences
Available options 
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Clayton
Co-supervisors 
Dr 
Sunil Sapkota

Want to apply for this project? Submit an Expression of Interest by clicking on Contact the researcher.