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Childhood determinants of midlife brain health

Description 
A number of studies have linked mid- and late-life vascular risk factors to poorer cognitive function. However, little is known about childhood risk factors (or change in these factors) that might be associated with subsequent cognition at midlife. Aims: To examine if childhood fitness is associated with midlife cognitive function To examine if cardiometabolic factors in childhood are associated with midlife cognitive function To examine if menstrual, reproductive or sex hormone levels are associated with midlife cognitive function Data from the Australian Health and Fitness Survey (AHFS 1985) and the Childhood Determinants of Health (CDAH) study will be used for this project. AHFS participants were aged between 7-15 years (n=8,498) and by CDAH-3 they were aged 36-46 years (n=1281 with cognitive data). Determination of vascular risk factor effects in the earlier stages of life could inform the design of more targeted and effective interventions for healthy cognitive aging.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
brain health, cognition, childhood, midlife, cardiometabolic, vascular health
School 
Central Clinical School » Medicine - Peninsula
Available options 
PhD/Doctorate
Honours
Time commitment 
Full-time
Part-time
Top-up scholarship funding available 
No
Physical location 
Peninsula Health
Co-supervisors 
Ms 
Taya Collyer
Assoc Prof 
Seana Gall

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