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Biomarkers of Endometriosis

Description 
This project will examine serum and saliva for endometriosis biomarkers that diagnose and stratify for disease severity and related infertility. The project will profile glycosylation changes to the proteins produced by the endometrium lining of the uterus, to identify the unique disease associated glycoforms. The project will utilise lectins and agglutinins as tools to examine both human endometrial tissue and secretions using histochemical and western blot techniques. Complimenting this will be an affinity-proteomic study in collaboration with Baker IDI to identify individual protein glycosylation changes for subsequent validation in an antibody-based assay of patient samples.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
endometriosis, diagnostic, biomarkers, glycosylation
School 
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research » Molecular and Translational Sciences
Available options 
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Short projects
Time commitment 
Full-time
Part-time
Top-up scholarship funding available 
No
Physical location 
Monash Medical Centre Clayton

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