Association between diet and cancer incidence and survival in older adults

The ASPREE trial enrolled community dwelling 19411 older adults and explored whether low-dose could prolong disability-free survival. The study continued past the trial phase, into an observational study, following the original cohort. A wide range of demographic, anthropometric and health outcomes has been collected throughout the study, including cancer outcomes, a secondary endpoint of the trial. Additionally, one sub study (ALSOP) has also collected a food frequency questionnaire (food types, amounts and frequencies), at various time points throughout. There are known associations between diet and cancer risk, mainly with respect to processed foods and red meats. This project would look at identifying food patterns associated with increased or decreased cancer risk, by cancer type and stage. This rich dataset would enable explorations of overarching diet types, as well as in-depth food categories.