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Are immunometabolic processes perturbed in chronic inflammatory disease?

Description 
It has become increasingly clear that immune cells can change their metabolic state in response to activation in order to meet their energy requirements, however much less is known about the metabolic condition of immune cells in disease settings. The aim of this project will be to investigate immunometabolic processes in immune cells from mice harbouring chronic inflammatory diseases. The student will be involved in immune cell purification, advanced biochemical methods and imaging flow cytometry.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
immunometabolism; metabolic pathways; glycolysis; oxidative phosphorylation; mucosal inflammatory disease
School 
Central Clinical School » Immunology and Pathology
Available options 
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Alfred Research Alliance
Co-supervisors 
Dr 
Evelyn Tsantikos

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