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Antidepressants and post-traumatic epilepsy

Description 
In addition to living with this challenging neurological disorder, many people with epilepsy also suffer from mood disorders such as depression. Typically, patients would be treated with antidepressants in these cases, but little is known about how antidepressants impact the underlying disease of epilepsy. Our recent evidence suggests synergistic biological effects, such that antidepressants accelerate epilepsy onset and progression. This project will explore the impact of antidepressants on epilepsy risk in a rat model of traumatic brain injury. The hypothesis is that treatment with SSRI antidepressants increases the likelihood of epilepsy following traumatic brain injury.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
antidepressant, fluoxetine, epilepsy, depression, traumatic brain injury, rat model, neuroscience, , physiology ,pharmacology, microbiology, anatomy, developmental biology, molecular biology, biochemistry, immunology, human pathology, clinical
School 
Central Clinical School » Neuroscience
Available options 
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Alfred Centre

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