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Advanced MRI for monitoring neurological disease

Description 
Magnetic Resonance Imaging (MRI) represents the gold standard for radiological diagnosis and monitoring of neurological diseases such as multiple sclerosis. However, current clinical MRI technologies are not sensitive to the primary pathologies that drive neurological progression: axonal demyelination and degeneration. Nor can they reveal reparative processes such as axonal remyelination, axonal remodelling and brain network remodelling. This project will address the following problems to improve radiological practice: 1: How to measure pathological and reparative changes in axonal myelination? 2: How to measure loss of axons? 3: How to identify stressed neurons that are at risk of degeneration? 4: How to classify pathology and stratify patients? 5: How to identify pathological and reparative changes in large scale brain networks? 6: How to translate new imaging biomarkers into radiological practice? If you are interested in developing new ways to acquire and analyse MRI, and to translate this knowledge into new clinical tools, please get in touch to discuss more specific projects.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
magnetic resonance imaging, neurological diseases
School 
Central Clinical School » Neuroscience
Available options 
PhD/Doctorate
Masters by research
Masters by coursework
Honours
BMedSc(Hons)
Time commitment 
Full-time
Top-up scholarship funding available 
Yes
Year 1: 
$5000
Year 2: 
$5000
Year 3: 
$5000
Physical location 
Alfred Centre
Co-supervisors 
Prof 
Meng Law

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