Description
Systemic Lupus Erythematous is a complex heterogeneous disease in which the pathogenesis remains poorly understood. The measurement of immune proteins and gene expression in biological samples allows a precision medicine approach in SLE. We host a large contemporary cohort of SLE patients linked to extensive biobanking, providing a rich database for analysis of research questions on clinical outcomes. Thousands of serum samples and peripheral blood mRNA samples are on hand linked to deep clinical annotation, to help solve translational questions in this disease.
We are currently analysing data from a massive multi-omics study including whole genome sequencing, RNASeq, proteomics, metabolomics, and wide angle autoantibody screening from a multinational cohort of 800 SLE patients. Projects to develop new clinical tests are also part of our overall plan
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
lupus, SLE, systemic lupus erythematosus, clinical, biomarkers, informatics, precision medicine, proteomics, genomics
School
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research » Medicine - Monash Medical Centre
Available options
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Short projects
Time commitment
Full-time
Part-time
Top-up scholarship funding available
No
Physical location
Monash Health Translation Precinct (Monash Medical Centre)
Co-supervisors
Dr
Fabien Vincent