Description
Traditionally, the ischemic penumbra has been analyses using volumetric approach. It is defined as perfusion deficit on Tmax minus infarct core defined by CBV or CBF on CT or MR perfusion. Information on neuroanatomy and vascular anatomy (https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.123.046083)
are not used in this approach. Here we propose a voxel-based approach (https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.120.032867) to evaluate the ischemic penumbra taking into account non contrast CT in addition to CBV or CBF in to measure infarct core.
The student will learn about image analysis, especially voxel-based analysis.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
stroke, infarct core, penumbra, CT perfusion
School
School of Clinical Sciences at Monash Health / Hudson Institute of Medical Research » Medicine - Monash Medical Centre
Available options
PhD/Doctorate
Honours
BMedSc(Hons)
Time commitment
Full-time
Top-up scholarship funding available
No
Physical location
Monash Medical Centre Clayton
Co-supervisors
Prof
Henry Ma
Dr
Jason Vuong