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Identifying the role of platelet changes in response to hypoxia or Cyanotic Heart Defects

Description 
Platelets are the key cells involved in haemostasis and thrombosis. As they traverse the bloodstream, they experience varying degrees of oxygen saturation. However, in ischemia, ischemia-reperfusion, or cyanotic heart defects, they will experience hypoxia. We have developed a unique microfluidic tool to investigate platelet changes in real-time using live cell imaging. The goal is to fully characterise functional changes in platelets, the pathways, and what this means for bleeding and thrombosis in vulnerable patient populations.
Essential criteria: 
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords 
Platelets, hypoxia, ischemia, ischemia-reperfusion, cyanotic heart defects, oxygen, microfluidics
School 
Victorian Heart Institute (VHI)
Available options 
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Time commitment 
Full-time
Top-up scholarship funding available 
No
Physical location 
Victorian Heart Hospital

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